Research progress inpostoperative brachytherapy for cervical cancer / 中华放射肿瘤学杂志

Radiotherapy is an important part of the postoperative adjuvant therapy of cervical cancer. Along with the persistent development of radiotherapy techniques, the application of brachytherapy has been more and more used as a boost to external beam radiotherapy. In this artical, the indications of postoperative radiotherapy and the application of brachytherapy were reviewed.

Research progress inpostoperative brachytherapy for cervical cancer / 中华放射肿瘤学杂志

Radiotherapy is an important part of the postoperative adjuvant therapy of cervical cancer.Along with the persistent development of radiotherapy techniques,the application of brachytherapy has been more and more used as a boost to external beam radiotherapy.In this artical,the indications of postoperative radiotherapy and the application of brachytherapy were reviewed.

Effect of hypoxia on epithelial growth factor receptor expression and cell apoptosis of breast cancer and cervical cancer xenografts in nude mice / 中华放射肿瘤学杂志

Objective To observe the effect of hypoxia on the expression of epithelial growth factor receptor (EGFR) and cell apoptosis of breast and cervical cancer xenografts in nude mouse models.Methods The nude mouse models with MCF-7 and HeLa xenografts were established.The degree of hypoxia and EGFR expression were observed by confocal microscopy.The influence of EGFR expression on cell apoptosis under hypoxia was observed by TUNEL assay.Results EGFR expression was either up-regulated or down-regulated in the MCF-7 and HeLa cells with high degree of hypoxia.Furthermore,the degree of apoptosis was reduced in tumor tissues with high EGFR expression compared with that in those with low expression of EGFR.Conclusion The hypoxia in MCF-7 and HeLa cells exerts heterogeneous effect on EGFR expression.Under hypoxic conditions,EGFR exoression is negatively correlated with cell apoptosis.

Interpretation of ICRU Report No.89 (prescribing, recording, and reporting brachytherapy for cancer of the cervix)—radiobiology / 中华放射肿瘤学杂志

This paper made a detailed interpretation about the radiobiology-related contents in the ICRU report No.89,aiming to provide reference to resolve the problems related to radiobiology for the colleagues occupied in the brachytherapy for cervical cancer.

Interpretation of ICRU report No.89-radiation physics / 中华放射肿瘤学杂志

In this article,the content of radiation physics in the ICRU report No.89 were interpreted in details,aiming to provide reference in the radiation physics for radiologists performing brachytherapy for cervical cancer patients.